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According to NPR pharmaceuticals correspondent Sydney Lupkin, the FDA Adverse Event Reporting System (FAERS) has received at least 489 reports of patients experiencing anxiety, depression or suicidal thoughts while taking drugs like Ozempic that contain the active ingredient Semaglutide

Serious events remain rare with proper screening and monitoring

PMID 21306239

February 2026 marked a meaningful expansion in the oral GLP-1 landscape, with new data adding to the momentum that began with the FDA approval of oral Wegovy (semaglutide 25 mg tablets) in late 2025

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Next, we detected that the levels of ampk were dramatically elevated in the LMNA (R453W) fish treated with creatine for 1 month (Fig